兔抗IGF2R(Phospho-Ser2409) 多克隆抗体

Background:

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Applications:

WB, IHC

Name of antibody:

IGF2R(Phospho-Ser2409)

Immunogen:

Peptide sequence around phosphorylation site of Serine 2409(Q-D-S(p)-E-D) derived from Human IGF2R.

Full name:

insulin-like growth factor 2 receptor

Synonyms：

MPR1; MPRI; CD222; CIMPR; M6P-R

SwissProt:

P11717

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

274 kDa

WB Positive control:

COS7 cells lysates treated with UV

WB Recommended dilution:

500-1000