Background: 
					 
						This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. 
					 
						Applications: 
					 
						ELISA, WB 
					 
						Name of antibody: 
					 
						HTRA2 
					 
						Immunogen: 
					 
						Synthetic peptide of human HTRA2 
					 
						Full name: 
					 
						HtrA serine peptidase 2 
					 
						Synonyms: 
					 
						OMI; MGCA8; PARK13; PRSS25 
					 
						SwissProt: 
					 
						O43464 
					 
						ELISA Recommended dilution: 
					 
						5000-10000 
					 
						WB Predicted band size: 
					 
						49 kDa 
					 
						WB Positive control: 
					 
						Rat brain tissue, Mouse brain tissue, Raji and 231 cell lysates 
					 
						WB Recommended dilution: 
					 
						500-2000 
					
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