兔抗CASP6多克隆抗体

Background:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Applications:

ELISA, WB

Name of antibody:

CASP6

Immunogen:

Fusion protein of human CASP6

Full name:

Caspase 6, apoptosis-related cysteine peptidase

Synonyms：

MCH2

SwissProt:

P55212

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

33 kDa

WB Positive control:

Mouse stomach tissue

WB Recommended dilution:

200-1000