小鼠抗IL36G单克隆抗体

Background:

The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IHC, IF

Name of antibody:

IL36G

Immunogen:

Fusion protein of human IL36G

Full name:

interleukin 36, gamma (IL36G), transcript variant 1

Synonyms:

IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2

SwissProt:

Q9NZH8

IHC positive control:

human pancreas tissue and adenocarcinoma of human colon tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

19 kDa

WB Positive control:

MCF7 cell lysate

WB Recommended dilution:

200-1000