兔抗HSPA2多克隆抗体

Background:

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells.

Applications:

ELISA, WB, IHC

Name of antibody:

HSPA2

Immunogen:

Fusion protein of human HSPA2

Full name:

heat shock protein family A (Hsp70) member 2

Synonyms:

HSP70-2; HSP70-3

SwissProt:

P54652

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

70 kDa

WB Positive control:

231 cell, Hela cell, Jurkat cell, A549 cell, NIH/3T3 cell, Human cerebrum tissue, Mouse brain tissue lysates

WB Recommended dilution:

500-2000