兔抗GPR68多克隆抗体

Background:

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer By similarity.

Applications:

WB

Name of antibody:

GPR68

Immunogen:

Synthesized peptide derived from internal of human SPR1.

Full name:

G protein-coupled receptor 68

Synonyms：

OGR1; GPR12A

SwissProt:

Q15743

WB Predicted band size:

41 kDa

WB Positive control:

Jurkat cells and Hela cells lysates

WB Recommended dilution:

500-3000