小鼠抗ICAM3单克隆抗体

Background:

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

ICAM3

Immunogen:

Fusion protein of human ICAM3

Full name:

intercellular adhesion molecule 3 (ICAM3)

Synonyms:

CD50; CDW50; ICAM-R

SwissProt:

P32942

IHC positive control:

carcinoma of human lung tissue and adenocarcinoma of human breast tissue; human lymph node tissue and human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

60 kDa

WB Positive control:

A549, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

200-1000