小鼠抗CPB2单克隆抗体

Background:

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun

Applications:

IHC

Name of antibody:

CPB2

Immunogen:

Fusion protein of human CPB2

Full name:

carboxypeptidase B2 (plasma) (CPB2), transcript variant 1

Synonyms:

CPU; PCPB; TAFI

SwissProt:

Q96IY4

IHC positive control:

carcinoma of human lung tissue

IHC Recommend dilution:

30-150