小鼠抗COX6C单克隆抗体

Background:

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul

Applications:

WB, IHC, IF

Name of antibody:

COX6C

Immunogen:

Fusion protein of human COX6C

Full name:

cytochrome c oxidase subunit VIc (COX6C)

Synonyms:

cytochrome c oxidase subunit VIc preprotein; cytochrome c oxidase subunit VIc

SwissProt:

P09669

IHC positive control:

adenocarcinoma of human ovary tissue and human pancreas tissue; adenocarcinoma of human endometrium tissue and adenocarcinoma of human breast tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

9 kDa

WB Positive control:

NIH/3T3 cell, Mouse brain tissue, Mouse liver tissue, Mouse spleen tissue lysates

WB Recommended dilution:

200-1000