兔抗KLRC1多克隆抗体

Background:

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Applications:

ELISA, IHC

Name of antibody:

KLRC1

Immunogen:

Fusion protein of human KLRC1

Full name:

killer cell lectin-like receptor subfamily C, member 1

Synonyms:

NKG2; NKG2A; CD159A

SwissProt:

P26715

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

50-200