小鼠抗AKT3单克隆抗体

Background:

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.

Applications:

WB, IHC, IF, FC

Name of antibody:

AKT3

Immunogen:

Fusion protein of human AKT3

Full name:

v-akt murine thymoma viral oncogene homolog 3 (AKT3), transcript variant 1

Synonyms:

MPPH; MPPH2; PKB-GAMMA; PKBG; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2

SwissProt:

Q9Y243

IHC positive control:

human lung tissue

IHC Recommend dilution:

10-50

WB Predicted band size:

56 kDa

WB Positive control:

SVT2 and PC12 cell lysate

WB Recommended dilution:

200-1000