兔抗CFI多克隆抗体

Background:

This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes.

Applications:

WB

Name of antibody:

CFI

Immunogen:

Synthesized peptide derived from internal of human CFI.

Full name:

complement factor I

Synonyms：

FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA

SwissProt:

P05156

WB Predicted band size:

66 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000