兔抗CDC27多克隆抗体

Background:

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Applications:

ELISA, WB, IHC

Name of antibody:

CDC27

Immunogen:

Synthetic peptide of human CDC27

Full name:

cell division cycle 27

Synonyms：

APC3; HNUC; NUC2; ANAPC3; CDC27Hs; D0S1430E; D17S978E

SwissProt:

P30260

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

92 kDa

WB Positive control:

HepG2 and K562 cells

WB Recommended dilution:

500-2000