兔抗CD44多克隆抗体

Background:

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Applications:

ELISA, IHC

Name of antibody:

CD44

Immunogen:

Synthetic peptide of human CD44

Full name:

CD44 molecule (Indian blood group)

Synonyms:

IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III

SwissProt:

P16070

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and Human ovarian cancer

IHC Recommend dilution:

50-100