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中文名称： SHPK 抗原（重组蛋白）
英文名称： SHPK Antigen (Recombinant Protein)
别 名： sedoheptulokinase; SHK; CARKL
储 存： 冷冻（-20℃）
相关类别：抗原
技术规格
|
Full name: |
sedoheptulokinase |
|
Synonyms: |
SHK; CARKL |
|
Swissprot: |
Q9UHJ6 |
|
Gene Accession: |
BC020543 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. |
