中文名称:TBP 抗原(重组蛋白)
英文名称:TBP Antigen (Recombinant Protein)
相关类别:抗原
储 存: 冷冻(-20℃)
概 述
技术规格
| Background: | This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Expression system: | Escherichia coli | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Gene Accession: | BC109054 | 
| Swissprot: | P20226 | 
| Synonyms: | HDL4; GTF2D; SCA17; TFIID; GTF2D1 | 
| Full name: | TATA box binding protein | 
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