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中文名称 : 小鼠抗NANP单克隆抗体
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Background: |
Sialic acids are a family of 9-carbon 2-keto-3-deoxy sugars that are found on the ends of glycoproteins and glycolipids and play important roles in recognition events within the cell. Playing an important role in cell-cell and protein-protein recognition, N-acetylneuraminate is the main form of sialic acid in vertebrates. NANP (N-acylneuraminate-9-phosphatase), also known as HDHD4 (Haloacid dehalogenase-like hydrolase domain-containing protein 4), is a 248 amino acid protein that belongs to the haloacid dehalogenase (HAD) family and is responsible for dephosphorylating Neu5Ac-9-phosphate to form N-acetylneuraminate. Characteristic of the HAD phosphatase family, the catalytic activity of NANP is dependent upon the presence of magnesium and is inhibited by vanadate and calcium. |
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Applications: |
WB, IHC |
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Name of antibody: |
NANP |
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Immunogen: |
Fusion protein of human NANP |
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Full name: |
N-acetylneuraminic acid phosphatase (NANP) |
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Synonyms: |
C20orf147; dJ694B14.3; HDHD4 |
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SwissProt: |
Q8TBE9 |
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IHC positive control: |
human prostate tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
28 kDa |
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WB Positive control: |
Jurkat cell lysate |
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WB Recommended dilution: |
500-2000 |
