兔抗CCNC(Phospho-Ser275)多克隆抗体

Background:

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Applications:

WB, IHC

Name of antibody:

CCNC(Phospho-Ser275)

Immunogen:

Peptide sequence around phosphorylation site of Serine 275(N-G-S(p)-A-N) derived from Human Cyclin C.

Full name:

cyclin C

Synonyms：

CycC

SwissProt:

P24863

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

33 kDa

WB Positive control:

NIH/3T3 cells, A549 cells and Hela cells lysates

WB Recommended dilution:

500-1000