兔抗CYB5R3多克隆抗体

Background:

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Applications:

ELISA, IHC

Name of antibody:

CYB5R3

Immunogen:

Synthetic peptide of human CYB5R3

Full name:

cytochrome b5 reductase 3

Synonyms:

B5R; DIA1

SwissProt:

P00387

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

30-150