| Background: | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. | 
| Applications: | WB, IHC | 
| Name of antibody: | TRADD | 
| Immunogen: | Synthesized peptide derived from Internal of human TRADD. | 
| Full name: | TNFRSF1A-associated via death domain | 
| Synonyms: | Hs.89862 | 
| SwissProt: | Q15628 | 
| IHC positive control: | Human breast carcinoma tissue | 
| IHC Recommend dilution: | 50-100 | 
| WB Predicted band size: | 34 kDa | 
| WB Positive control: | COS7 cells lysate | 
| WB Recommended dilution: | 500-3000 | 
	
	

 
 
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