| Background: | Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. | 
| Applications: | ELISA, WB, IHC | 
| Name of antibody: | TLE1 | 
| Immunogen: | Fusion protein of human TLE1 | 
| Full name: | transducin like enhancer of split 1 | 
| Synonyms: | ESG; ESG1; GRG1 | 
| SwissProt: | Q04724 | 
| ELISA Recommended dilution: | 5000-10000 | 
| IHC positive control: | Human cervical cancer | 
| IHC Recommend dilution: | 30-150 | 
| WB Predicted band size: | 83 kDa | 
| WB Positive control: | Human fetal liver tissue lysate | 
| WB Recommended dilution: | 200-1000 | 
	
	

 
 
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