兔抗APLF多克隆抗体

Background:

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

Applications:

ELISA, IHC

Name of antibody:

APLF

Immunogen:

Fusion protein of human APLF

Full name:

aprataxin and PNKP like factor

Synonyms：

APFL; PALF; Xip1; C2orf13

SwissProt:

Q8IW19

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

25-100