兔抗GRIN2B(Phospho-Tyr1336)多克隆抗体

Background:

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B).

Applications:

WB

Name of antibody:

GRIN2B(Phospho-Tyr1336)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine1336 (S-P-Y(p)-A-H) derived from Human NMDAR2B.

Full name:

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Synonyms：

MRD6; NR2B; hNR3; GluN2B; NMDAR2B

SwissProt:

Q13224

WB Predicted band size:

166 kDa

WB Positive control:

Jurkat cells lysates treated with TNF

WB Recommended dilution:

500-1000