兔抗GPSM2多克隆抗体

Background:

The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

GPSM2

Immunogen:

Synthetic peptide of human GPSM2

Full name:

G protein signaling modulator 2

Synonyms:

LGN; CMCS; PINS; DFNB82

SwissProt:

P81274

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

30-150