兔抗SPINK7多克隆抗体

Background:

SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.

Applications:

ELISA, IHC

Name of antibody:

SPINK7

Immunogen:

Synthetic peptide of human SPINK7

Full name:

serine peptidase inhibitor, Kazal type 7 (putative)

Synonyms：

ECG2; ECRG2

SwissProt:

P58062

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer and Human lung cancer

IHC Recommend dilution:

25-100