兔抗FH多克隆抗体

Background:

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Applications:

ELISA, WB, IHC

Name of antibody:

FH

Immunogen:

Fusion protein of human FH

Full name:

fumarate hydratase

Synonyms：

MCL; LRCC; HLRCC; MCUL1

SwissProt:

P07954

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

55 kDa

WB Positive control:

Mouse liver, brain and heart tissue, RAW264.7 cells

WB Recommended dilution:

500-2000