兔抗FHIT多克隆抗体

Background:

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

FHIT

Immunogen:

Fusion protein of human FHIT

Full name:

fragile histidine triad

Synonyms：

FRA3B, AP3Aase

SwissProt:

P49789

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

17 kDa

WB Positive control:

Human fetal kidney tissue

WB Recommended dilution:

200-1000