兔抗EGFR多克隆抗体

Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

EGFR

Immunogen:

Synthetic peptide of human EGFR

Full name:

epidermal growth factor receptor

Synonyms：

ERBB, HER1, mENA, ERBB1, PIG61

SwissProt:

P00533

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

134 kDa

WB Positive control:

Mouse liver tissue, Hela and A549 cells

WB Recommended dilution:

200-1000