兔抗BMPR1B多克隆抗体

Background:

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Applications:

ELISA, IHC

Name of antibody:

BMPR1B

Immunogen:

Fusion protein of human BMPR1B

Full name:

bone morphogenetic protein receptor, type IB

Synonyms：

ALK6; ALK-6; CDw293

SwissProt:

O00238

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human gastric cancer

IHC Recommend dilution:

25-100