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  • PTPRK抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW19507
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: PTPRK抗原(重组蛋白)

英文名称: PTPRK Antigen (Recombinant Protein)

别     名:  R-PTP-kappa

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Full length fusion protein

技术规格

Full name:

protein tyrosine phosphatase, receptor type, K

Synonyms:

R-PTP-kappa

Swissprot:

Q15262

Gene Accession:

BC063596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.