兔抗EPOR(Ab-426) 多克隆抗体

Background:

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

Applications:

WB

Name of antibody:

EPOR(Ab-426)

Immunogen:

Synthesized peptide derived from Internal of human Epo-R.

Full name:

erythropoietin receptor

Synonyms：

EPO-R

SwissProt:

P19235

WB Predicted band size:

55 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000