兔抗EDA2R多克隆抗体

Background:

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

EDA2R

Immunogen:

Fusion protein of human EDA2R

Full name:

ectodysplasin A2 receptor

Synonyms：

XEDAR; EDAA2R; EDA-A2R; TNFRSF27

SwissProt:

Q9HAV5

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

33 kDa

WB Positive control:

293T cells

WB Recommended dilution:

500-2000