兔抗EPS15L1多克隆抗体

Background:

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Applications:

ELISA, WB, IHC

Name of antibody:

EPS15L1

Immunogen:

Fusion protein of human EPS15L1

Full name:

epidermal growth factor receptor pathway substrate 15-like 1

Synonyms：

EPS15R

SwissProt:

Q9UBC2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human colon cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

94 kDa

WB Positive control:

Hela, PC3, 231 and 293T cells

WB Recommended dilution:

500-2000