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021-54845833/15800441009
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Background: |
Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EPS15L1 |
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Immunogen: |
Fusion protein of human EPS15L1 |
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Full name: |
epidermal growth factor receptor pathway substrate 15-like 1 |
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Synonyms： |
EPS15R |
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SwissProt: |
Q9UBC2 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human colon cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
94 kDa |
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WB Positive control: |
Hela, PC3, 231 and 293T cells |
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WB Recommended dilution: |
500-2000 |
