兔抗DDX3Y多克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified.

Applications:

IHC

Name of antibody:

DDX3Y

Immunogen:

Synthesized peptide derived from internal of human DDX3Y.

Full name:

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

Synonyms：

DBY

SwissProt:

O15523

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100