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021-54845833/15800441009
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Full name: |
NUMB endocytic adaptor protein |
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Synonyms: |
S171; C14orf41; c14_5527 |
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Swissprot: |
P49757 |
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Gene Accession: |
BC020788 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. |
