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  • LAT2抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW16758
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中文名称: LAT2抗原(重组蛋白)

英文名称: LAT2 Antigen (Recombinant Protein)

别       名: LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 27-243 amino acids of human LAT2

技术规格

Full name:

linker for activation of T cells family, member 2

Synonyms:

LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15

Swissprot:

Q9GZY6

Gene Accession:

BC001609

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.