中文名称: SIGLEC5抗原(重组蛋白)
英文名称: SIGLEC5 Antigen (Recombinant Protein)
别 名:CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 19-229 amino acids of human SIGLEC5 | 
| Full name: | sialic acid binding Ig-like lectin 5 | 
| Synonyms: | CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5 | 
| Swissprot: | O15389 | 
| Gene Accession: | BC029896 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. | 
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