中文名称:AK2抗原(重组蛋白)
英文名称: AK2 Antigen (Recombinant Protein)
别 名: ADK2; AK 2
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 2-203 amino acids of human AK2 | 
| Full name: | adenylate kinase 2 | 
| Synonyms: | ADK2; AK 2 | 
| Swissprot: | P54819 | 
| Gene Accession: | BC009405 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2. | 
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