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中文名称： EDA2R抗原（重组蛋白）
英文名称： EDA2R Antigen (Recombinant Protein)
别 名： XEDAR; EDAA2R; EDA-A2R; TNFRSF27
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from C terminal 138 amino acids of human EDA2R |
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Full name: |
ectodysplasin A2 receptor |
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Synonyms: |
XEDAR; EDAA2R; EDA-A2R; TNFRSF27 |
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Swissprot: |
Q9HAV5 |
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Gene Accession: |
BC034919 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene. |
