中文名称:BAAT抗原(重组蛋白)
英文名称: BAAT Antigen (Recombinant Protein)
别 名: BAT; BACAT
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to C terminal 250 amino acids of human BAAT | 
| Full name: | bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) | 
| Synonyms: | BAT; BACAT | 
| Swissprot: | Q14032 | 
| Gene Accession: | BC009567 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. | 
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