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中文名称：CPE 抗原（重组蛋白）
英文名称：CPE Antigen (Recombinant Protein)
别 名： carboxypeptidase E; CPH
储 存： 冷冻（-20℃）
相关类别：抗原
技术规格
|
Full name: |
carboxypeptidase E |
|
Synonyms: |
CPH |
|
Swissprot: |
P16870 |
|
Gene Accession: |
BC033866 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. |
