中文名称: ZUP1 抗原(重组蛋白)
英文名称: ZUP1 Antigen (Recombinant Protein)
别 名: zinc finger containing ubiquitin peptidase 1; DUB; ZUFSP; C6orf113
相关类别: 抗原
储 存: 冷冻(-20℃)
概 述
| Full name: | zinc finger containing ubiquitin peptidase 1 | 
| Synonyms: | DUB; ZUFSP; C6orf113 | 
| Swissprot: | Q96AP4 | 
| Gene Accession: | BC016879 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018] | 
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