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021-54845833/15800441009
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Fusion protein corresponding to a region derived from 294-493 amino acids of human DUS2 |
技术规格
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Full name: |
dihydrouridine synthase 2 |
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Synonyms: |
SMM1; DUS2L; URLC8 |
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Swissprot: |
Q9NX74 |
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Gene Accession: |
BC006527 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. |
