兔抗COL15A1多克隆抗体

Background:

This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.

Applications:

ELISA, IHC

Name of antibody:

COL15A1

Immunogen:

Synthetic peptide of human COL15A1

Full name:

collagen, type XV, alpha 1

SwissProt:

P39059

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain

IHC Recommend dilution:

25-100