| Background: | This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. | 
| Applications: | WB | 
| Name of antibody: | TEK(Phospho-Tyr992) | 
| Immunogen: | Peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y(p)-V-K) derived from Human TIE2. | 
| Full name: | TEK tyrosine kinase, endothelial | 
| Synonyms: | TIE2; VMCM; TIE-2; VMCM1; CD202B | 
| SwissProt: | Q02763 | 
| WB Predicted band size: | 126 kDa | 
| WB Positive control: | HepG2 cells lysates | 
| WB Recommended dilution: | 500-1000 | 
	
	 
 
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