小鼠抗RBBP5单克隆抗体

Background:

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Applications:

WB, IF

Name of antibody:

RBBP5

Immunogen:

Fusion protein of human RBBP5

Full name:

RB binding protein 5, histone lysine methyltransferase complex subunit

Synonyms:

RBQ3; SWD1

SwissProt:

Q15291

WB Predicted band size:

59 kDa

WB Positive control:

C2C12, THP-1, PC12 and 3T3 cell lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

50-100