兔抗MMP3多克隆抗体

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Applications:

ELISA, IHC

Name of antibody:

MMP3

Immunogen:

Fusion protein of human MMP3

Full name:

Matrix metalloproteinase-3

Synonyms：

SL-1, STMY, STR1, CHDS6, MMP-3, STMY1

SwissProt:

P08254

ELISA Recommended dilution:

500-5000

IHC positive control:

Human breast cancer and Human cervical cancer

IHC Recommend dilution:

25-100