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021-54845833/15800441009
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Background: |
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The Ly-6 alloantigens represent a family of phosphatidylinositol anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 expression is commonly induced on T and B lymphocytes after activation by mitogens. Ly-6A/E is a phosphatidylinositol-linked transmembrane member of the Ly-6 family that is produced in humans after 4 weeks of age. ?-interferon and TNF regulate Ly-6A/E at the level of transcription and mRNA stabilization in certain thymocytes and T-cells. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
Ly6a |
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Immunogen: |
Synthetic peptide of mouse Ly6a |
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Full name: |
lymphocyte antigen 6 complex, locus A |
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Synonyms: |
TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1 |
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SwissProt: |
P05533 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Mouse liver |
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IHC Recommend dilution: |
20-100 |
