兔抗KRT81多克隆抗体

Background:

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Applications:

ELISA, WB, IHC

Name of antibody:

KRT81

Immunogen:

Fusion protein of human KRT81

Full name:

keratin 81

Synonyms:

HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1

SwissProt:

Q14533

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human thyroid cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

55 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

200-1000