兔抗KBTBD8多克隆抗体

Background:

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.

Applications:

ELISA, WB

Name of antibody:

KBTBD8

Immunogen:

Fusion protein of human KBTBD8

Full name:

kelch repeat and BTB domain containing 8

Synonyms:

TAKRP; TA-KRP

SwissProt:

Q8NFY9

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

69 kDa

WB Positive control:

NIH/3T3 cell lysate

WB Recommended dilution:

1000-5000